August 2022 – Ponik lab graduate student, Metti Gari, successfully completed her preliminary exam, “PEG-FUD as an anti-cancer therapy for breast cancer”. She is now a dissertation in the Molecular and Cellular Pharmacology Program at …
Month: August 2022
The Ponik and Kwon labs collaborate to improve the tumor targeting potential of an anti-fibrotic inhibitor of fibronectin assembly.
August 2022. In this study we demonstrated improved tumor targeting and biodistribution of 20-kDa PEG conjugated FUD peptide (PEG-FUD) in the 4T1 murine breast cancer model using multimodal imaging techniques. We demonstrate that PEGylation improves …
Ponik Lab publishes new methods protocol to use endogenous fluorescence to segment intravital images.
May 2022. This novel method demonstrates an intravital imaging workflow pairing collagen second harmonic generation imaging, endogenous fluorescence from the metabolic co-factor NAD(P)H, and fluorescence lifetime imaging microscopy (FLIM) as a means to non-invasively compartmentalize the …