About Our Lab

Breast cancer is one type of solid tumor for which the extracellular matrix plays an integral role in disease progression. Increased deposition and remodeling of the extracellular matrix in the tumor microenvironment provides both biochemical and biophysical cues for cancer cells. The Ponik lab is interested in better understanding the specific signaling pathways that are regulated by cell interactions with the extracellular matrix, and how these pathways are involved in the progression of breast cancer.

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