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Ponik Lab News & Events

Erica Hoffman presents at the 2023 Midwest TME Meeting

Posted on November 25, 2023

May 2023 – Erica Hoffman is selected for an oral presentation at the 2023 Midwest TME meeting at Purdue University.

Posted in Ponik Lab News & Events

Congratulations to Metti Gari!

Posted on August 25, 2022

August 2022 – Ponik lab graduate student, Metti Gari, successfully completed her preliminary exam, “PEG-FUD as an anti-cancer therapy for breast cancer”. She is now a dissertation in the Molecular and Cellular Pharmacology Program at …

Posted in Ponik Lab News & Events, Uncategorized

The Ponik and Kwon labs collaborate to improve the tumor targeting potential of an anti-fibrotic inhibitor of fibronectin assembly.

Posted on August 25, 2022

August 2022. In this study we demonstrated improved tumor targeting and biodistribution of 20-kDa PEG conjugated FUD peptide (PEG-FUD) in the 4T1 murine breast cancer model using multimodal imaging techniques. We demonstrate that PEGylation improves …

Posted in Ponik Lab News & Events, Uncategorized

Ponik Lab publishes new methods protocol to use endogenous fluorescence to segment intravital images.

Posted on August 25, 2022

May 2022. This novel method demonstrates an intravital imaging workflow pairing collagen second harmonic generation imaging, endogenous fluorescence from the metabolic co-factor NAD(P)H, and fluorescence lifetime imaging microscopy (FLIM) as a means to non-invasively compartmentalize the …

Posted in Ponik Lab News & Events, Uncategorized

Congrats to Metti Gari! Winner of the 2022 ASMB image contest

Posted on March 8, 2022

“Every Rose has a Fiber”  The extracellular matrix in a mouse model of triple negative breast cancer.  (Tenascin-C = red, Fibronectin = green, DAPI = blue)

Posted in Ponik Lab News & Events, Uncategorized

Ponik Lab publishes study on directional cues in the tumor microenvironment

Posted on May 7, 2021

May 2021. In this study we developed innovative methodology to discover that collagen alignment results in a 35-fold difference in cell-scale stiffness and alters contractile force transmission through the fiber network. Furthermore, we identified bias …

Posted in Ponik Lab News & Events

Ponik Lab Welcomes New Students!

Posted on December 18, 2020

December 2020: The Ponik lab welcomees two new graduate students. Metti Gari is a student in the Molecular and Cellular Pharmacology Program and Shelby Fertal is in the Endocrinology and Reproductive Physiology Program.  We are …

Posted in Ponik Lab News & Events

Congratulations to Erica Hoffmann!

Posted on August 7, 2020

August 2020 – Ponik lab grad student, Erica Hoffmann, successfully completed her prelim exam, “The Regulation of Tumor-Associated Macrophages by a Collagen-Dense Breast Tumor Microenvironment”. She is now a dissertator in the Molecular and Cellular …

Posted in Ponik Lab News & Events

Ponik Lab publishes review article on biomechanical activation of tumor associated macrophages

Posted on May 20, 2020

May 2020.  In this review article we highlight the importance of investigating how the extracellular matrix directly and indirectly impacts tumor-associated macrophage activation. Recent advances in investigating macrophages in the tumor microenvironment and future directions …

Posted in Ponik Lab News & Events

The Ponik and Weaver labs publish new study on a live cell reporter of exosomes

Posted on May 6, 2020

April 2020.  The finding of this study, published in Nature Communications, demonstrates through dynamic monitoring of EVs that exosomes are secreted at the front of migrating cells and left behind in exosome trails. We also …

Posted in Ponik Lab News & Events
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